[SOURCES]
The regulatory frameworks behind chemply’s compliance data — which lists are covered, how many substances each holds, and when they were last refreshed.
The U.S. TSCA Inventory; a listing means the substance is an existing chemical permitted in U.S. commerce.
TSCA Section 8(a)(7) PFAS reporting; a listing means manufacturers and importers must report the substance to EPA as a PFAS.
EPA's CompTox PFAS inventory (explicit structures); a listing identifies the substance as a per- or polyfluoroalkyl substance.
FDA indirect food additives (21 CFR); a listing means the substance is permitted in food-contact materials under defined conditions.
EPA's CompTox PFAS inventory (UVCB substances); a listing identifies the substance as a per- or polyfluoroalkyl substance.
FDA Food Contact Notifications; a listing means the substance has an effective notification authorising a specific food-contact use.
FDA-approved drug substances; a listing means the substance is an approved active pharmaceutical ingredient.
California Proposition 65; a listing means the substance is known to the state to cause cancer or reproductive harm and requires a warning.
Hazardous air pollutants under the U.S. Clean Air Act; a listing means emissions of the substance are federally regulated.
EPA's Toxics Release Inventory; a listing means facilities must publicly report releases and transfers of the substance.
EPA's Safer Chemical Ingredients List; a listing means the substance is recognised as a safer choice within its functional class.
EPA's chemical evaluation and prioritisation network; a listing means the substance is being tracked for screening and risk prioritisation.
EPA's Endocrine Disruptor Screening Program; a listing means the substance is being screened for potential effects on the hormone system.
FDA GRAS substances; a listing means the substance is Generally Recognized As Safe for its intended use in food.
Risk management under TSCA Section 6; a listing means EPA is restricting the substance's manufacture or use due to unreasonable risk.
PBT chemicals addressed under TSCA Section 6(h); a listing means the substance is persistent, bioaccumulative, and toxic and faces use restrictions.
EPA's national drinking-water rule for PFAS; a listing means the substance has an enforceable maximum contaminant level in public water.
EPA's CompTox chemicals dashboard; a listing means the substance has curated chemistry, exposure, and hazard data in EPA's database (informational, not a restriction).
EPA's former master PFAS list (now retired); a listing flagged the substance as a per- or polyfluoroalkyl substance.
Substances in U.S. but not Canadian commerce; a listing means lighter notification requirements than a fully new substance.
Canada's inventory of substances already in commerce; a listing means it can be manufactured or imported without new-substance notification.
Canada's Significant New Activity provisions; a listing means any new use of the substance triggers mandatory notification and assessment.
Canada's pollutant-release inventory; a listing means facilities must publicly report releases and transfers of the substance.
Canada's CEPA list of toxic substances; a listing flags the substance as toxic and subject to federal risk-management controls.
Canada's PFAS assessment under CEPA; a listing identifies the substance as a per- or polyfluoroalkyl substance under review.
Canada's prohibition of certain toxic substances; a listing means manufacture, use, sale, or import is banned or strictly limited.
Canada's asbestos ban; a listing means the substance is a form of asbestos prohibited from import, sale, and use.
Canada's WHMIS 2015 workplace system; a listing assigns the substance GHS hazard categories requiring labels and safety data sheets.
The EU's classification, labelling and packaging rules; a listing assigns the substance harmonised hazard classes such as carcinogenic, toxic, or corrosive.
EU prohibited cosmetic substances (Annex II); a listing means the substance is banned from cosmetic products.
Medicines authorised in the EU; a listing means the substance is an approved active ingredient in a human or veterinary medicine.
EU restricted cosmetic substances (Annex III); a listing means the substance is allowed only under specified conditions and concentration limits.
The REACH SVHC Candidate List; a listing identifies the substance as of very high concern, triggering disclosure duties and possible authorisation.
EU permitted cosmetic colorants (Annex IV); a listing means the substance is an allowed colorant, subject to stated conditions.
REACH Restrictions (Annex XVII); a listing means the substance's manufacture, use, or sale is restricted under defined conditions.
The REACH Authorisation List (Annex XIV); a listing means the substance may not be used in the EU after its sunset date without specific authorisation.
EU permitted cosmetic preservatives (Annex V); a listing means the substance is an allowed preservative within set limits.
The EU Water Framework Directive priority list; a listing means the substance is a priority pollutant with environmental quality standards for surface water.
The EU Drinking Water Directive positive list; a listing means the substance is approved for materials in contact with drinking water.
ECHA's persistence and bioaccumulation assessment; a listing identifies the substance as PBT or vPvB, raising long-term environmental concern.
EU permitted cosmetic UV filters (Annex VI); a listing means the substance is an allowed sunscreen filter within set limits.
The EU Persistent Organic Pollutants regulation; a listing means the substance is banned or severely restricted as a POP.
The EU Prior Informed Consent regulation; a listing means exports require notification because the substance is banned or severely restricted elsewhere.
The EU RoHS Directive; a listing means the substance is restricted in electrical and electronic equipment.
The EU cosmetic-ingredient database; a listing records the substance's regulatory status and intended function in cosmetics.
The EU Deforestation Regulation; a listing means products containing the substance require deforestation-free due diligence to enter the EU.
The EU Detergents Regulation; a listing covers the substance's permitted use and labelling in detergent products.
The EU food-contact plastics rule (10/2011); a listing means the substance is authorised for food-contact plastics, subject to migration limits.
The EU Toy Safety Directive; a listing means the substance is restricted or concentration-limited in toys.
Great Britain's mandatory classification & labelling; a listing assigns the substance legally binding GB hazard classifications.
The UK REACH SVHC Candidate List; a listing identifies the substance as of very high concern under UK REACH.
The UK REACH Restriction List; a listing means the substance's use is restricted under defined conditions in Great Britain.
The UK REACH Authorisation List; a listing means the substance needs authorisation for continued use in Great Britain.
Australia's official workplace hazard classification; a listing assigns the substance harmonised GHS health and physical-hazard categories.
Australia's industrial-chemicals inventory (AIIC); a listing means the substance is approved for industrial use in Australia.
Japan's official GHS hazard classification (NITE); a listing assigns the substance harmonised GHS health and physical-hazard categories.
The WHO/IARC carcinogen classification; a listing assigns the substance a cancer-hazard group, e.g. Group 1 (carcinogenic to humans).
The Rotterdam Convention; a listing means international trade in the substance requires the prior informed consent of importing countries.
The Stockholm Convention; a listing means the substance is a persistent organic pollutant slated for global elimination or restriction.
Codex Alimentarius residue limits; a listing sets the maximum residue of the substance (e.g. a pesticide) permitted in specific foods.
The UN Globally Harmonized System (Rev. 11); a listing gives the substance its internationally recommended hazard classification and labelling.
OSPAR's priority-action list; a listing means the substance is targeted for ending discharges to the North-East Atlantic.
France's endocrine-disruptor list; a listing means the substance is identified or suspected as an endocrine disruptor.
New Zealand's HSNO hazard classification; a listing assigns the substance GHS hazard categories under NZ law.
The New Zealand Inventory of Chemicals; a listing means the substance is approved for use in New Zealand.
Switzerland's food-contact materials rules; a listing means the substance is permitted in food-contact materials under Swiss law.
Switzerland's ORRChem; a listing means the substance is prohibited or restricted on the Swiss market.