[SOURCES]
The regulatory frameworks behind chemply’s compliance data — which lists are covered, how many substances each holds, and when they were last refreshed.
| Framework | Substances | Updated | Status |
|---|---|---|---|
| TSCA Inventory[tsca] | 70,345 | 2026-06-04 | Loaded |
| EPA TSCA Section 8(a)(7) PFAS Reporting[tsca_pfas_8a7] | 13,035 | 2026-06-05 | Loaded |
| EPA CompTox PFAS — explicit structures (PFASSTRUCT)[epa_pfas_struct] | 5,997 | 2026-06-05 | Loaded |
| EPA CompTox PFAS — UVCB substances (PFASDEV)[epa_pfas_dev] | 2,631 | 2026-06-05 | Loaded |
| FDA Approved Drug Substances[fda_drug] | 1,000 | 2026-06-08 | Loaded |
| California Proposition 65[prop65] | 947 | 2026-06-08 | Loaded |
| EPA Hazardous Air Pollutants (Clean Air Act)[epa_caa] | 183 | 2026-06-08 | Loaded |
| EPA Toxic Release Inventory (TRI)[epa_tri] | 60 | 2026-06-08 | Loaded |
| EPA Safer Chemical Ingredients List (SCIL)[epa_scil] | 41 | 2026-06-08 | Loaded |
| EPA Chemical Evaluation and Prioritization Network[epa_cepn] | 40 | 2026-06-08 | Loaded |
| EPA Endocrine Disruptor Screening Program[epa_edsp] | 40 | 2026-06-08 | Loaded |
| FDA GRAS Substances[fda_gras] | 36 | 2026-06-08 | Loaded |
| TSCA Section 6 Risk Management[epa_tsca6] | 9 | 2026-06-08 | Loaded |
| EPA PBT Chemicals (TSCA Section 6(h))[epa_pbt] | 7 | 2026-06-08 | Loaded |
| EPA PFAS National Primary Drinking Water Regulation[epa_pfas_npdwr] | 6 | 2026-06-08 | Loaded |
| EPA CompTox Chemicals Dashboard[epa_comptox] | — | 2026-04-02 | Pending |
| EPA PFAS Master List (RETIRED)[epa_pfas_master] | — | — | Pending |
| FDA Indirect Food Additives (21 CFR 170-199)[fda_21cfr] | — | — | Pending |
| FDA Food Contact Notifications (FCN)[fda_fcn] | — | — | Pending |
| Framework | Substances | Updated | Status |
|---|---|---|---|
| Canada Non-Domestic Substances List[canada_ndsl] | 50,581 | 2026-06-08 | Loaded |
| Canada Domestic Substances List[canada_dsl] | 28,626 | 2026-06-08 | Loaded |
| Canada Significant New Activity (SNAc)[canada_snac] | 498 | 2026-06-08 | Loaded |
| Canada National Pollutant Release Inventory (NPRI)[canada_npri] | 475 | 2026-06-08 | Loaded |
| Canada CEPA Schedule 1 (Toxic Substances)[canada_cepa_sched1] | 345 | 2026-06-08 | Loaded |
| Canada Prohibition of Certain Toxic Substances (2012)[canada_prohibited_2012] | 209 | 2026-06-08 | Loaded |
| Canada Prohibition of Asbestos Regulations[canada_asbestos] | 7 | 2026-06-08 | Loaded |
| Canada PFAS Assessment (CEPA)[canada_pfas] | — | — | Pending |
| Canada WHMIS 2015 GHS Classification[canada_whmis] | — | — | Pending |
| Framework | Substances | Updated | Status |
|---|---|---|---|
| CLP Regulation (EC) 1272/2008[clp] | 4,397 | 2026-06-08 | Loaded |
| EU Cosmetics – Prohibited substances (Annex II)[eu_cosm_prohibited] | 1,690 | 2026-06-08 | Loaded |
| EMA Authorised Medicines (EPAR)[ema_medicines] | 1,607 | 2026-06-08 | Loaded |
| EU Cosmetics – Restricted substances (Annex III)[eu_cosm_restricted] | 358 | 2026-06-08 | Loaded |
| REACH SVHC Candidate List[reach_svhc] | 200 | 2026-06-08 | Loaded |
| EU Cosmetics – Allowed colorants (Annex IV)[eu_cosm_colorants] | 151 | 2026-06-08 | Loaded |
| REACH Restrictions (Annex XVII)[reach_annex_xvii] | 79 | 2026-06-08 | Loaded |
| REACH Authorisation List (Annex XIV)[reach] | 59 | 2026-06-08 | Loaded |
| EU Cosmetics – Allowed preservatives (Annex V)[eu_cosm_preservatives] | 55 | 2026-06-08 | Loaded |
| EU Water Framework Directive Priority Substances[eu_wfd] | 52 | 2026-06-08 | Loaded |
| ECHA PBT Assessment[echa_pbt] | 34 | 2026-06-08 | Loaded |
| EU Cosmetics – Allowed UV filters (Annex VI)[eu_cosm_uv_filters] | 31 | 2026-06-08 | Loaded |
| EU POPs Regulation (EU) 2019/1021[eu_pops] | 30 | 2026-06-08 | Loaded |
| EU PIC Regulation (EU) 649/2012[eu_pic] | 27 | 2026-06-08 | Loaded |
| EU RoHS Directive 2011/65/EU[eu_rohs] | 10 | 2026-06-08 | Loaded |
| EU CosIng – Cosmetics Ingredient Database[eu_cosing] | — | — | Pending |
| EU Deforestation Regulation (EU) 2023/1115[eu_deforestation] | — | — | Pending |
| EU Detergents Regulation (EC) 648/2004[eu_detergents] | — | — | Pending |
| EU Drinking Water Directive Positive List[eu_dwd] | — | — | Pending |
| EU Food Contact Materials Regulation 10/2011[eu_fcm] | — | — | Pending |
| EU Toy Safety Directive 2009/48/EC[eu_toy_safety] | — | — | Pending |
| Framework | Substances | Updated | Status |
|---|---|---|---|
| IARC Carcinogen Classification[iarc] | 1,110 | 2026-06-08 | Loaded |
| Rotterdam Convention on PIC[rotterdam_pic] | 52 | 2026-06-08 | Loaded |
| Stockholm Convention on POPs[stockholm_pops] | 30 | 2026-06-08 | Loaded |
| Codex Alimentarius Maximum Residue Limits[codex_mrls] | — | — | Pending |
| GHS Revision 11 (2025)[ghs_rev11] | — | — | Pending |
| Framework | Substances | Updated | Status |
|---|---|---|---|
| UK REACH SVHC Candidate List[uk_reach_svhc] | 295 | 2026-06-08 | Loaded |
| GB Mandatory Classification & Labelling[gb_mcl] | — | — | Pending |
| UK REACH Authorisation List (Annex 14)[uk_reach_auth] | — | — | Pending |
| UK REACH Restriction List (Annex 17)[uk_reach_restrict] | — | — | Pending |
| Framework | Substances | Updated | Status |
|---|---|---|---|
| OSPAR List of Chemicals for Priority Action[ospar] | 42 | 2026-06-08 | Loaded |
| Framework | Substances | Updated | Status |
|---|---|---|---|
| Australia AICIS/AIIC[au_aicis] | — | — | Pending |
| Australia Safe Work GHS Classification (HCIS)[au_swa_ghs] | — | — | Pending |
| Framework | Substances | Updated | Status |
|---|---|---|---|
| France Endocrine Disruptor List[france_ed] | — | — | Pending |
| Framework | Substances | Updated | Status |
|---|---|---|---|
| New Zealand HSNO GHS Classification[nz_hsno_ghs] | — | — | Pending |
| New Zealand Inventory of Chemicals (NZIoC)[nz_nzioc] | — | — | Pending |
| Framework | Substances | Updated | Status |
|---|---|---|---|
| Switzerland BLV Food Contact Materials[swiss_blv_fcm] | — | — | Pending |
| Switzerland ORRChem Restricted Substances[swiss_orrchem] | — | — | Pending |