Aspirin

CAS 50-78-2·C9H8O4·180.16 g/mol·6 listings across 4 jurisdictions.

Also known as aspirin, vetality, acetyl salicylate, aspirin pain relief … +15 more

CAS
50-78-2
Mol. Weight
180.16000 g/mol
InChIKey
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
SMILES
CC(=O)Oc1ccccc1C(=O)O
PubChem CID
2244

Regulatory
Status

6 entries across 4 jurisdictions. Sourced from EU, US, UK and international regulatory databases.

Overall compliance

Restricted — high concern

High-concern classification in 2 of 5 frameworks, across 4 jurisdictions.

United StatesUnited States[US]
FDA Approved Drug Substances
FDA DRUG
Approved
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FDA-approved drug substances; a listing means the substance is an approved active pharmaceutical ingredient.

{
  "source": "openFDA NDC (active ingredients)",
  "cas_number": "",
  "chemical_name": "ASPIRIN",
  "product_count": 811,
  "active_ingredient": "ASPIRIN"
}
California Proposition 65
PROP65
Listed
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California Proposition 65; a listing means the substance is known to the state to cause cancer or reproductive harm and requires a warning.

{
  "source": "OEHHA Proposition 65 List",
  "cas_number": "50-78-2",
  "date_listed": "1990-07-01 00:00:00",
  "nsrl_or_madl": "",
  "chemical_name": "Aspirin (NOTE:  It is especially  important not to use aspirin during the last three months of pregnancy,  unless specifically directed to do so by a physician because it may cause  problems in the unborn child or  complications during delivery.)",
  "type_of_toxicity": "developmental, female",
  "listing_mechanism": "SQE"
}
TSCA Inventory
TSCA
Listed
View →

The U.S. TSCA Inventory; a listing means the substance is an existing chemical permitted in U.S. commerce.

{
  "name": "Benzoic acid, 2-(acetyloxy)-",
  "flags": "",
  "status": "active",
  "cas_number": "50-78-2",
  "risk_level": "low"
}
European UnionEuropean Union[EU]
EU REACH Registered Substances
EU REACH REGISTERED
Listed
View →
{
  "source": "EU REACH Registered Substances (ECHA CHEM)",
  "ec_number": "200-064-1",
  "cas_number": "50-78-2",
  "chemical_name": "O-acetylsalicylic acid"
}
United KingdomUnited Kingdom[UK]
Not ListedNot listed in any United Kingdom framework on record.
International[INTERNATIONAL]
Not ListedNot listed in any International framework on record.
CanadaCanada[CANADA]
Canada Domestic Substances List
CANADA DSL
Listed
View →

Canada's inventory of substances already in commerce; a listing means it can be manufactured or imported without new-substance notification.

{
  "source": "Canada Domestic Substances List (DSL)",
  "cas_number": "50-78-2",
  "identifier": "50-78-2",
  "publication": "Canada Gazette Part II, Vol. 128, No. 9, May 4, 1994, SOR/94-311 (http://central.bac-lac.gc.ca/.redirect?app=cangaz&id=14339&lang=eng)",
  "identifier_2": "",
  "chemical_name": "Benzoic acid, 2-(acetyloxy)-",
  "additional_information": "This substance is on the Domestic Substances List (DSL). \n \nThis substance was added to the DSL as an “Existing Substance” given that it meets the criteria set out in the Canadian Environmental Protection Act, 1999 for substances that were in commerce in Canada between 1984 and 1986."
}
AustraliaAustralia[AUSTRALIA]
Not ListedNot listed in any Australia framework on record.
New ZealandNew Zealand[NEW ZEALAND]
Not ListedNot listed in any New Zealand framework on record.
FranceFrance[FRANCE]
Not ListedNot listed in any France framework on record.
SwitzerlandSwitzerland[SWITZERLAND]
Not ListedNot listed in any Switzerland framework on record.
NE-Atlantic[NE-ATLANTIC]
Not ListedNot listed in any NE-Atlantic framework on record.
JapanJapan[JAPAN]
Japan NITE GHS Classification
JP NITE GHS
Listed
View →

Japan's official GHS hazard classification (NITE); a listing assigns the substance harmonised GHS health and physical-hazard categories.

{
  "source": "Japan NITE-CMC (via PubChem GHS Classification)",
  "cas_number": "50-78-2",
  "pictograms": [],
  "pubchem_cid": "2244",
  "signal_word": "Danger",
  "chemical_name": "ASA",
  "hazard_statements": [
    "H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]",
    "H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]",
    "H302: Harmful if swallowed [Warning Acute toxicity, oral]",
    "H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]",
    "H360: May damage fertility or the unborn child [Danger Reproductive toxicity]",
    "H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]",
    "H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]",
    "H316: Causes mild skin irritation [Warning Skin corrosion/irritation]",
    "H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure]",
    "H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]"
  ]
}

Data as of 2026-10-26·All sources and refresh dates

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