Glyphosate

CAS 994-61-6·C3H8NO5P·169.07 g/mol·9 listings across 7 jurisdictions.

Also known as CID 59310676, glyphosat, gliphosate, glyphosate … +15 more

CAS
994-61-6
Mol. Weight
169.07000 g/mol
InChIKey
XDDAORKBJWWYJS-UHFFFAOYSA-N
SMILES
O=C(O)C[NH2+]CP(=O)([O-])O
PubChem CID
3496
PubChem CID
59310676

Regulatory
Status

9 entries across 7 jurisdictions. Sourced from EU, US, UK and international regulatory databases.

Overall compliance

Restricted — high concern

High-concern classification in 7 of 9 frameworks, across 7 jurisdictions.

United StatesUnited States[US]
EPA Endocrine Disruptor Screening Program
EPA EDSP
Listed
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EPA's Endocrine Disruptor Screening Program; a listing means the substance is being screened for potential effects on the hormone system.

{
  "tier": "1",
  "notes": "Herbicide",
  "cas_number": "1071-83-6",
  "chemical_name": "Glyphosate"
}
California Proposition 65
PROP65
Listed
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California Proposition 65; a listing means the substance is known to the state to cause cancer or reproductive harm and requires a warning.

{
  "source": "OEHHA Proposition 65 List",
  "cas_number": "1071-83-6",
  "date_listed": "2017-07-07 00:00:00",
  "nsrl_or_madl": "1100",
  "chemical_name": "Glyphosate",
  "type_of_toxicity": "cancer",
  "listing_mechanism": "LC"
}
European UnionEuropean Union[EU]
CLP Regulation (EC) 1272/2008
CLP
Listed
View →

The EU's classification, labelling and packaging rules; a listing assigns the substance harmonised hazard classes such as carcinogenic, toxic, or corrosive.

{
  "source": "ECHA CLP Annex VI (harmonised C&L)",
  "index_no": "607-315-00-8",
  "ec_number": "213-997-4",
  "cas_number": "1071-83-6",
  "hazard_class": "Eye Dam. 1\nAquatic Chronic 2",
  "chemical_name": "glyphosate (ISO); N-(phosphonomethyl)glycine",
  "hazard_statements": "H318\nH411"
}
EU Water Framework Directive Priority Substances
EU WFD
Listed
View →

The EU Water Framework Directive priority list; a listing means the substance is a priority pollutant with environmental quality standards for surface water.

{
  "annex": "Watch",
  "notes": "Herbicide",
  "cas_number": "1071-83-6",
  "chemical_name": "Glyphosate",
  "priority_status": "Watch List"
}
United KingdomUnited Kingdom[UK]
GB Mandatory Classification & Labelling
GB MCL
Listed
View →

Great Britain's mandatory classification & labelling; a listing assigns the substance legally binding GB hazard classifications.

{
  "source": "GB MCL (HSE)",
  "ec_number": "213-997-4",
  "cas_number": "1071-83-6",
  "hazard_class": "Eye Dam. 1; Aquatic Chronic 2",
  "chemical_name": "glyphosate (ISO);",
  "hazard_statements": "H318; H411"
}
International[INTERNATIONAL]
IARC Carcinogen Classification
IARC
Listed
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The WHO/IARC carcinogen classification; a listing assigns the substance a cancer-hazard group, e.g. Group 1 (carcinogenic to humans).

{
  "source": "IARC Monographs",
  "volume": "112",
  "cas_number": "1071-83-6",
  "iarc_group": "2A",
  "chemical_name": "Glyphosate",
  "evaluation_year": "2015"
}
CanadaCanada[CANADA]
Canada Domestic Substances List
CANADA DSL
Listed
View →

Canada's inventory of substances already in commerce; a listing means it can be manufactured or imported without new-substance notification.

{
  "source": "Canada Domestic Substances List (DSL)",
  "cas_number": "1071-83-6",
  "identifier": "1071-83-6",
  "publication": "Canada Gazette Part II, Vol. 128, No. 9, May 4, 1994, SOR/94-311 (http://central.bac-lac.gc.ca/.redirect?app=cangaz&id=14339&lang=eng)",
  "identifier_2": "",
  "chemical_name": "Glycine, N-(phosphonomethyl)-",
  "additional_information": "This substance is on the Domestic Substances List (DSL). \n \nThis substance was added to the DSL as an “Existing Substance” given that it meets the criteria set out in the Canadian Environmental Protection Act, 1999 for substances that were in commerce in Canada between 1984 and 1986."
}
AustraliaAustralia[AUSTRALIA]
Australia Safe Work GHS Classification (HCIS)
AU SWA GHS
Listed
View →

Australia's official workplace hazard classification; a listing assigns the substance harmonised GHS health and physical-hazard categories.

{
  "source": "Safe Work Australia HCIS (via PubChem GHS Classification)",
  "cas_number": "1071-83-6",
  "pictograms": [],
  "pubchem_cid": "3496",
  "signal_word": "Danger",
  "chemical_name": "GPF",
  "hazard_statements": [
    "H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]",
    "H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]"
  ]
}
New ZealandNew Zealand[NEW ZEALAND]
Not ListedNot listed in any New Zealand framework on record.
FranceFrance[FRANCE]
Not ListedNot listed in any France framework on record.
SwitzerlandSwitzerland[SWITZERLAND]
Not ListedNot listed in any Switzerland framework on record.
NE-Atlantic[NE-ATLANTIC]
Not ListedNot listed in any NE-Atlantic framework on record.
JapanJapan[JAPAN]
Japan NITE GHS Classification
JP NITE GHS
Listed
View →

Japan's official GHS hazard classification (NITE); a listing assigns the substance harmonised GHS health and physical-hazard categories.

{
  "source": "Japan NITE-CMC (via PubChem GHS Classification)",
  "cas_number": "1071-83-6",
  "pictograms": [],
  "pubchem_cid": "3496",
  "signal_word": "Danger",
  "chemical_name": "GPF",
  "hazard_statements": [
    "H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]",
    "H351: Suspected of causing cancer [Warning Carcinogenicity]",
    "H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]",
    "H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]",
    "H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]",
    "H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]",
    "H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]",
    "H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]",
    "H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]"
  ]
}

Data as of 2026-10-26·All sources and refresh dates

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